STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gtpbp1GTP-binding protein 1; Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity. HNRNPD, HNRNPR and SYNCRIP. Identified in a complex with HNRNPD, HNRNPL, HNRNPQ,HNRNPR, HNRNPU and AANAT mRNA, but does not bind mRNA by itself. superfamily. Classic translation factor GTPase family. GTPBP1 subfamily. domain; sp|D2XV59|GTPB1_RAT;evalue=1e-062; PctID=31.29; score=241. (529 aa)    
Predicted Functional Partners:
rpl13/rps9
Fused L13/S9 ribosomal protein; L13 protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity). the 30S ribosomal subunit (By similarity). protein L13P family. protein S9P family. ribosomal subunit, and that they are not known to contact each other in the ribosome, this may be incorrectly predicted and should perhaps be two separate genes; sp|O26146|RLSX_METTH;evalue=9e-049; PctID=71.43; score=191.
  
 0.999
rpl13
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 0.999
eif2a
Translation initiation factor 2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
   
 0.979
rps3
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 0.977
rps5
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
 
 0.976
rps6e
30S ribosomal protein S6e; sp|O26360|RS6E_METTH;evalue=4e-036; PctID=57.94; score=149; {ECO:0000255|HAMAP-Rule:MF_00512}; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.974
rps10
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
 
 0.970
rps2
30S ribosomal protein S2; sp|O26150|RS2_METTH;evalue=1e-095; PctID=84.85; score=348; Belongs to the universal ribosomal protein uS2 family.
  
 0.970
rps4e
30S ribosomal protein S4e; sp|O26123|RS4E_METTH;evalue=1e-098; PctID=69.71; score=358; Belongs to the eukaryotic ribosomal protein eS4 family.
   
 0.970
rps12
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
 
 0.969
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.