STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
trm1tRNA (guanine(26)-N(2))-dimethyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (393 aa)    
Predicted Functional Partners:
MCBB_0978
THUMP domain-containing protein; tr|F6D2L1|F6D2L1_METPW;evalue=4e-023; PctID=37.79; score=113; {ECO:0000313|EMBL:AEG17945,1}.
    
 
 0.816
MCBB_0979
THUMP domain-containing protein; tr|F6D2L2|F6D2L2_METPW;evalue=7e-032; PctID=61.02; score=142; {ECO:0000313|EMBL:AEG17946,1}.
    
 
 0.816
MCBB_2063
Putative NOP5 family protein MJ0694; sp|Q58105|Y694_METJA;evalue=6e-049; PctID=38.70; score=195.
 
    0.784
pus10
tRNA pseudouridine synthase Pus10; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
 
   
 0.770
leuS
Leucine-tRNA ligase; sp|O27552|SYL_METTH;evalue=0.0; PctID=60.64; score=1246; {ECO:0000255|HAMAP-Rule:MF_00049}; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
   0.754
truB
Putative tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
 
 0.737
MCBB_2217
Putative protein methyltransferase using S-adenosyl-L-methionine as the methyl donor. May methylate a Gln residue in target proteins (By similarity). family; sp|Q58338|Y928_METJA;evalue=2e-042; PctID=48.63; score=172.
    
 
 0.681
trmG10
tRNA (guanine(10)-N2)-dimethyltransferase; Catalyzes the adenosylmethionine-dependent methylation of the exocyclic amino group (N(2)) of guanosine at position 10 of various tRNAs. Acts via a two-step process that leads to the formation of either N(2)-monomethyl (m(2)G) or N(2)-dimethylguanosine (m(2)(2)G) (By similarity). tRNA = 2 S-adenosyl-L-homocysteine + N(2)-dimethylguanine(10) in tRNA. family. ProRule:PRU00529}; sp|O26820|TMG10_METTH;evalue=2e-076; PctID=43.60; score=286.
  
 
 0.677
rpoD
DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.643
rpoH
DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
  
   0.632
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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