STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fwdC3Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile (By similarity). + methanofuran + reduced acceptor. methenyl-5,6,7,8-tetrahydromethanopterin from CO(2): step 1/3. FwdE, FwdF and FwdG; sp|Q58571|FWDC_METJA;evalue=4e-020; PctID=40.77; score=98.2. (225 aa)    
Predicted Functional Partners:
glxD1
Glutamate synthase large subunit-like protein; sp|O87392|GLXD_RHIME;evalue=1e-085; PctID=51.92; score=317; Belongs to the glutamate synthase family.
 
  0.988
MCBB_0615
Archaeal glutamate synthase [NADPH]; sp|Q58746|AGLUS_METJA;evalue=3e-055; PctID=39.43; score=216; Belongs to the glutamate synthase family.
 
  0.981
glxD3
Glutamate synthase large subunit-like protein; sp|O87392|GLXD_RHIME;evalue=2e-083; PctID=49.38; score=310; Belongs to the glutamate synthase family.
  
 0.977
MCBB_1650
Putative glutamine amidotransferase MTH_191; sp|O26293|Y191_METTH;evalue=5e-137; PctID=79.67; score=487.
 
 
 0.975
glxC
sp|O87391|GLXC_RHIME;evalue=1e-020; PctID=31.98; score=99.8.
  
  
 
0.906
frhB1
Coenzyme F420 hydrogenase subunit beta; Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen. coenzyme F420. Name=Ni(2+); Xref=ChEBI:CHEBI:49786; Evidence=; Name=iron-sulfur cluster; Xref=ChEBI:CHEBI:30408; Evidence=; Note=There are 12-13 Fe atoms per alpha/beta/gamma unit of the FRH; Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence=; sp|Q60341|FRHB_METJA;evalue=5e-026; PctID=41.18; score=119.
  
    0.730
MCBB_2013
Transcriptional regulator; tr|U6ECU8|U6ECU8_9EURY;evalue=1e-057; PctID=59.67; score=228; {ECO:0000313|EMBL:CDG65805,1}.
       0.520
ileS
Isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
   
    0.514
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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