STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCBB_2073Putative protein MJ0414; sp|Q57857|Y414_METJA;evalue=6e-075; PctID=40.83; score=281. (404 aa)    
Predicted Functional Partners:
MCBB_1602
UPF0278 protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
     0.770
MCBB_2074
Putative protein MJ1225; sp|Q58622|Y1225_METJA;evalue=2e-018; PctID=27.69; score=93.2.
       0.674
MCBB_2075
Putative protein MJ1404; sp|Q58799|Y1404_METJA;evalue=2e-012; PctID=33.33; score=73.6.
 
     0.625
MCBB_2271
Putative protein MJ0575; sp|Q57995|Y575_METJA;evalue=2e-028; PctID=38.16; score=125.
 
     0.567
MCBB_0206
Putative 26S protease regulatory subunit homolog MTH_1011; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity); sp|O27092|PRS2_METTH;evalue=2e-129; PctID=63.27; score=462.
  
     0.566
pheA
Prephenate dehydratase; sp|Q58054|PHEA_METJA;evalue=1e-047; PctID=47.77; score=189.
       0.559
MCBB_2076
Putative protein MJ1225; sp|Q58622|Y1225_METJA;evalue=2e-055; PctID=39.72; score=216.
 
     0.543
polB2
DNA polymerase PolB subunit 2; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' exonuclease activity. diphosphate + DNA(n+1). protein A (RPA), while 3'-5' exonuclease activity is not. Polymerase inhibition can be overcome by replication factor C (RFC) and PCNA. Temperature dependence: Optimum temperature for DNA polymerase is 60 degrees Celsius, functional between 60 and 80 degrees Celsius. Exonuclease activity is higher at 70 than 50 degrees Celsius; exonuclease activity is associated with subunit 1. Probably binds replication protein A (RPA). split over 2 genes; [...]
 
    0.541
polB1
DNA polymerase PolB subunit 1; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' exonuclease activity. diphosphate + DNA(n+1). protein A (RPA), while 3'-5' exonuclease activity is not. Polymerase inhibition can be overcome by replication factor C (RFC) and PCNA. Temperature dependence: Optimum temperature for DNA polymerase is 60 degrees Celsius, functional between 60 and 80 degrees Celsius. Exonuclease activity is higher at 70 than 50 degrees Celsius; exonuclease activity is associated with subunit 1. Probably binds replication protein A (RPA). split over 2 genes; [...]
 
    0.528
MCBB_1586
Putative protein MTH_238; sp|O26340|Y238_METTH;evalue=2e-103; PctID=57.14; score=375.
  
     0.524
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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