STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCBB_21392,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase; Catalyzes an early step in riboflavin biosynthesis,the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate,yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate. ribitylamino)pyrimidin-4(3H)-one + NAD(P)(+) = 2, 5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one+ NAD(P)H; sp|O28272|RIB7_ARCFU;evalue=5e-010; PctID=28.87; score=64.7. (226 aa)    
Predicted Functional Partners:
MCBB_0498
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase; Catalyzes an early step in riboflavin biosynthesis,the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate,yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate. ribitylamino)pyrimidin-4(3H)-one + NAD(P)(+) = 2, 5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one+ NAD(P)H; sp|O26337|RIB7_METTH;evalue=2e-083; PctID=70.56; score=308.
  
  
 
0.909
arfB
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase; Catalyzes the hydrolysis of the formamide of 2-amino-5- formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy).
     
  0.900
MCBB_2138
Putative protein; tr|F6D4H9|F6D4H9_METPW;evalue=8e-044; PctID=53.12; score=182; {ECO:0000313|EMBL:AEG19219,1}.
       0.570
MCBB_2140
Uracil-DNA glycosylase; tr|A0A0F8QWG7|A0A0F8QWG7_9EURY;evalue=4e-049; PctID=53.19; score=200; {ECO:0000313|EMBL:KKH46896,1}.
       0.491
proG
Pyrroline-5-carboxylate reductase 3; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
     0.425
MCBB_2294
Divergent AAA domain family; tr|B1L0P2|B1L0P2_CLOBM;evalue=5e-095; PctID=45.04; score=354; {ECO:0000313|EMBL:ACA55039,1}.
  
     0.409
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.