STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCBB_2150TetR family transcriptional regulator; tr|K2R621|K2R621_METFO;evalue=2e-053; PctID=49.76; score=214; {ECO:0000313|EMBL:EKF86697,1}. (210 aa)    
Predicted Functional Partners:
emrB5
Multidrug export protein EmrB; Part of the tripartite efflux system EmrAB-TolC,which confers resistance to antibiotics such as CCCP, FCCP,2,4-dinitrophenol and nalidixic acid. composed of an inner membrane transporter, EmrB, a periplasmic membrane fusion protein, EmrA, and an outer membrane component, TolC. The complex forms a large protein conduit and can translocate molecules across both the inner and outer membranes. Interacts with EmrA. EmrAB complex forms a dimer in vitro; Multi-pass membrane protein family; sp|P0AEJ0|EMRB_ECOLI,sp|P0AEJ1|EMRB_ECO57;evalue=2e-039; PctID=26.02; sco [...]
       0.551
yttP
Putative HTH-type transcriptional regulator YttP; sp|O34970|YTTP_BACSU;evalue=1e-007; PctID=35.80; score=57.0.
  
     0.511
yerO
Putative HTH-type transcriptional regulator YerO; sp|O31500|YERO_BACSU;evalue=3e-007; PctID=45.61; score=55.1.
  
     0.445
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.