STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdtaS19Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=3e-019; PctID=31.67; score=97.1. (570 aa)    
Predicted Functional Partners:
pdtaR1
Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=1e-011; PctID=35.64; score=70.1.
   
 0.722
HK1
Putative histidine kinase 1; Cytokinin receptor related to bacterial two-component regulators. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. phospho-L-histidine. an active histidine that mediates the phosphotransfer. between a His in the transmitter domain and an Asp of the receiver domain. Sequence=BAD37425.1; Type=Erroneous gene model prediction; Evidence=; Sequence=BAD37547.1; Type=Erroneous gene model prediction; Evidence=; Sequence=BAF20158.1; Type=Erroneous gene model prediction; Evidence=; sp|A2YFR6|OHK1_ORYSI,sp|A3BE68|OHK1_ORYSJ; [...]
   
 0.722
pdtaR5
Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=4e-011; PctID=31.90; score=68.9.
   
 0.714
pdtaR3
Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=9e-016; PctID=31.88; score=85.1.
   
 0.700
phyR
Phyllosphere-induced regulator PhyR; Key regulator for adaptation to epiphytic life (leaf colonizing) of the bacterium. Positively regulates several genes including katE, sodA, hsp20, dps and gloA. However,it is not known whether this regulation is direct or indirect. Also induces several dehydrogenases. is the same as in the wild-type strain when plant colonization is mimicked in vitro in the presence of succinate and methanol. However, in planta colonization experiments show a severe growth defect of the phyR deletion mutant. Sequence=ACS40857.1; Type=Erroneous initiation; Evidence=; [...]
 
     0.573
MCBB_2315
Hypothetical protein.
       0.472
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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