STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). (274 aa)    
Predicted Functional Partners:
rnj
Ribonuclease J; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
      0.691
murC
UDP-N-acetylmuramate-L-alanine ligase; Cell wall formation. alanine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine. Rule:MF_00046}; sp|Q1GRY0|MURC_SPHAL;evalue=6e-007; PctID=33.33; score=56.2; {ECO:0000255|HAMAP-Rule:MF_00046}.
 
   
 0.630
rsmA
Putative ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
  
  
 0.619
MCBB_0439
Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; sp|O26830|MRAY_METTH;evalue=1e-092; PctID=55.05; score=340; {ECO:0000255|HAMAP-Rule:MF_00038}.
 
   
 0.552
uppS
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
   
 0.548
hmgA
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Converts HMG-CoA to mevalonate. hydroxy-3-methylglutaryl-CoA + 2 NADPH. biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3; sp|O26662|HMDH_METTH;evalue=3e-153; PctID=67.93; score=541.
      
 0.520
MCBB_0331
Mur ligase middle domain protein; tr|F6D2Z7|F6D2Z7_METPW;evalue=5e-120; PctID=52.19; score=438; {ECO:0000313|EMBL:AEG17360,1}.
     
 0.507
rpl13
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
     0.499
glmS
Glutamine-fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
  
 0.475
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
  
  
 0.475
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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