node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANF16984.1 | ANF17127.1 | XW81_00910 | XW81_01805 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.757 |
ANF16984.1 | ANF17163.1 | XW81_00910 | XW81_02035 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.868 |
ANF16984.1 | hisI | XW81_00910 | XW81_00500 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.682 |
ANF16984.1 | ilvC | XW81_00910 | XW81_02775 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.621 |
ANF16984.1 | ilvH | XW81_00910 | XW81_01050 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase 3 regulatory subunit; With IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.541 |
ANF16984.1 | leuD | XW81_00910 | XW81_02540 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.815 |
ANF16984.1 | metG | XW81_00910 | XW81_00515 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.512 |
ANF16984.1 | serC | XW81_00910 | XW81_01445 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.963 |
ANF16984.1 | thrA | XW81_00910 | XW81_00920 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
ANF16984.1 | thrB | XW81_00910 | XW81_00915 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |
ANF17127.1 | ANF16984.1 | XW81_01805 | XW81_00910 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.757 |
ANF17127.1 | ANF17163.1 | XW81_01805 | XW81_02035 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.715 |
ANF17127.1 | hisI | XW81_01805 | XW81_00500 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.735 |
ANF17127.1 | ilvC | XW81_01805 | XW81_02775 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.767 |
ANF17127.1 | ilvH | XW81_01805 | XW81_01050 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase 3 regulatory subunit; With IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.809 |
ANF17127.1 | leuD | XW81_01805 | XW81_02540 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.590 |
ANF17127.1 | metG | XW81_01805 | XW81_00515 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.546 |
ANF17127.1 | serC | XW81_01805 | XW81_01445 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.970 |
ANF17127.1 | thrA | XW81_01805 | XW81_00920 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.959 |
ANF17127.1 | thrB | XW81_01805 | XW81_00915 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.487 |