node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
L21_0162 | L21_0164 | L21_0162 | L21_0164 | Segregation and condensation protein A. | Hypothetical protein. | 0.847 |
L21_0162 | L21_2539 | L21_0162 | L21_2539 | Segregation and condensation protein A. | S-methyl-5'-thioinosine phosphorylase. | 0.450 |
L21_0162 | smc | L21_0162 | L21_0163 | Segregation and condensation protein A. | Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.999 |
L21_0164 | L21_0162 | L21_0164 | L21_0162 | Hypothetical protein. | Segregation and condensation protein A. | 0.847 |
L21_0164 | smc | L21_0164 | L21_0163 | Hypothetical protein. | Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.849 |
L21_0468 | kinA_4 | L21_0468 | L21_2494 | Sensory histidine kinase AtoS. | Sporulation kinase A. | 0.942 |
L21_0468 | smc | L21_0468 | L21_0163 | Sensory histidine kinase AtoS. | Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.928 |
L21_2539 | L21_0162 | L21_2539 | L21_0162 | S-methyl-5'-thioinosine phosphorylase. | Segregation and condensation protein A. | 0.450 |
L21_2539 | smc | L21_2539 | L21_0163 | S-methyl-5'-thioinosine phosphorylase. | Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.844 |
dbpA | recQ_2 | L21_2016 | L21_1521 | ATP-dependent RNA helicase DbpA. | ATP-dependent DNA helicase RecQ. | 0.932 |
dbpA | recQ_3 | L21_2016 | L21_1921 | ATP-dependent RNA helicase DbpA. | ATP-dependent DNA helicase RecQ. | 0.932 |
dbpA | smc | L21_2016 | L21_0163 | ATP-dependent RNA helicase DbpA. | Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.852 |
dbpA | topA | L21_2016 | L21_0924 | ATP-dependent RNA helicase DbpA. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.954 |
gyrB | recQ_2 | L21_2002 | L21_1521 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | ATP-dependent DNA helicase RecQ. | 0.819 |
gyrB | recQ_3 | L21_2002 | L21_1921 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | ATP-dependent DNA helicase RecQ. | 0.819 |
gyrB | smc | L21_2002 | L21_0163 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.901 |
gyrB | topA | L21_2002 | L21_0924 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.537 |
kinA_4 | L21_0468 | L21_2494 | L21_0468 | Sporulation kinase A. | Sensory histidine kinase AtoS. | 0.942 |
kinA_4 | smc | L21_2494 | L21_0163 | Sporulation kinase A. | Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.918 |
recQ_2 | dbpA | L21_1521 | L21_2016 | ATP-dependent DNA helicase RecQ. | ATP-dependent RNA helicase DbpA. | 0.932 |