| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| L21_0391 | rpoD | L21_0391 | L21_0065 | Coproporphyrinogen III oxidase. | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.469 |
| L21_0391 | rsmA | L21_0391 | L21_0296 | Coproporphyrinogen III oxidase. | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | 0.655 |
| L21_0391 | truA | L21_0391 | L21_1908 | Coproporphyrinogen III oxidase. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.745 |
| L21_0391 | truD | L21_0391 | L21_1994 | Coproporphyrinogen III oxidase. | tRNA pseudouridine synthase D; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.474 |
| L21_1907 | truA | L21_1907 | L21_1908 | Error-prone DNA polymerase. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.902 |
| L21_2511 | rpoD | L21_2511 | L21_0065 | Putative methanogenesis marker domain 9. | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.407 |
| L21_2511 | rsmA | L21_2511 | L21_0296 | Putative methanogenesis marker domain 9. | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | 0.444 |
| L21_2511 | truA | L21_2511 | L21_1908 | Putative methanogenesis marker domain 9. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.756 |
| L21_2511 | truB | L21_2511 | L21_2432 | Putative methanogenesis marker domain 9. | tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.617 |
| L21_2511 | truD | L21_2511 | L21_1994 | Putative methanogenesis marker domain 9. | tRNA pseudouridine synthase D; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.424 |
| adoK | truA | L21_1009 | L21_1908 | Adenosine kinase; Belongs to the carbohydrate kinase PfkB family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.767 |
| adoK | truB | L21_1009 | L21_2432 | Adenosine kinase; Belongs to the carbohydrate kinase PfkB family. | tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.734 |
| pus10 | rsmA | L21_0300 | L21_0296 | Putative pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | 0.879 |
| pus10 | truA | L21_0300 | L21_1908 | Putative pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.795 |
| pus10 | truB | L21_0300 | L21_2432 | Putative pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.776 |
| pus10 | truD | L21_0300 | L21_1994 | Putative pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | tRNA pseudouridine synthase D; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.807 |
| rpoD | L21_0391 | L21_0065 | L21_0391 | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | Coproporphyrinogen III oxidase. | 0.469 |
| rpoD | L21_2511 | L21_0065 | L21_2511 | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | Putative methanogenesis marker domain 9. | 0.407 |
| rpoD | rpsQ | L21_0065 | L21_2394 | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.986 |
| rpoD | rsmA | L21_0065 | L21_0296 | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | 0.650 |