STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrpLeucine-responsive regulatory protein. (143 aa)    
Predicted Functional Partners:
L21_0864
succinyl-CoA synthetase subunit alpha.
 
  
  0.922
sucD_2
Succinyl-CoA ligase [ADP-forming] subunit alpha.
    
  0.912
L21_2074
Hypothetical protein.
       0.839
L21_2073
Hypothetical protein.
       0.794
pdxK
Pyridoxine kinase.
    
  0.697
trpE
Anthranilate synthase component 1.
    
 0.678
truB
tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
    
  0.651
thiE
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
 0.644
gabD
Succinate-semialdehyde dehydrogenase [NADP(+)] GabD.
 
 
 0.569
thiDN
Bifunctional thiamine biosynthesis protein ThiDN.
 
  
  0.540
Your Current Organism:
Methanoculleus chikugoensis
NCBI taxonomy Id: 118126
Other names: DSM 13459, JCM 10825, M. chikugoensis, Methaniculleus sp. MG62, Methanoculleus chikugoensis Dianou et al. 2001, Methanoculleus sp. MG62, NBRC 101202, strain MG62
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