STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDX70852.1Kinase, pfkB family; [G] COG0524 Sugar kinases, ribokinase family. (328 aa)    
Predicted Functional Partners:
guaA
GMP synthase, C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.855
EDX74995.1
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase subfamily; [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.
 
 
 0.797
pgi
[G] COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.789
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.787
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.782
hisA
[E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase.
  
    0.777
glmS
Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.776
pfkA-2
Phosphofructokinase subfamily; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
 
 0.764
EDX72627.1
Alpha amylase, catalytic domain subfamily, putative; [G] COG0366 Glycosidases.
 
 
 0.761
EDX72582.1
Beta-ketoacyl synthase, N-terminal domain protein; [Q] COG3321 Polyketide synthase modules and related proteins.
  
 0.760
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
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