EDX76688.1 protein (Coleofasciculus chthonoplastes)

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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Score

EDX76688.1

Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase. (282 aa)

Predicted Functional Partners:

EDX70989.1

0.869

EDX76687.1

0.799

EDX75441.1

0.761

EDX71797.1

0.725

EDX78313.1

0.704

EDX71299.1

0.698

EDX77730.1

0.673

EDX75159.1

0.666

EDX71953.1

0.666

EDX71993.1

0.666

Your Current Organism:

Coleofasciculus chthonoplastes

NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDX70989.1	EDX71797.1	MC7420_6589	MC7420_6883	Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	Penicillin-binding protein, 1A family; [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein).	0.862
EDX70989.1	EDX71993.1	MC7420_6589	MC7420_5137	Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	Bacterial SH3 domain family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	0.624
EDX70989.1	EDX75441.1	MC7420_6589	MC7420_1359	Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	Transglycosylase SLT domain protein; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).	0.403
EDX70989.1	EDX76688.1	MC7420_6589	MC7420_1691	Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase.	0.869
EDX71299.1	EDX76688.1	MC7420_3414	MC7420_1691	Glycosyl hydrolase family 9; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase.	0.698
EDX71299.1	EDX78313.1	MC7420_3414	MC7420_8051	Glycosyl hydrolase family 9; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	Cna protein B-type domain; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	0.483
EDX71797.1	EDX70989.1	MC7420_6883	MC7420_6589	Penicillin-binding protein, 1A family; [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein).	Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	0.862
EDX71797.1	EDX75441.1	MC7420_6883	MC7420_1359	Penicillin-binding protein, 1A family; [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein).	Transglycosylase SLT domain protein; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).	0.628
EDX71797.1	EDX76688.1	MC7420_6883	MC7420_1691	Penicillin-binding protein, 1A family; [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein).	Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase.	0.725
EDX71953.1	EDX76688.1	MC7420_5097	MC7420_1691	Hypothetical protein.	Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase.	0.666
EDX71993.1	EDX70989.1	MC7420_5137	MC7420_6589	Bacterial SH3 domain family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	0.624
EDX71993.1	EDX76688.1	MC7420_5137	MC7420_1691	Bacterial SH3 domain family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase.	0.666
EDX75159.1	EDX76688.1	MC7420_2163	MC7420_1691	Bacterial SH3 domain family.	Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase.	0.666
EDX75441.1	EDX70989.1	MC7420_1359	MC7420_6589	Transglycosylase SLT domain protein; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).	Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	0.403
EDX75441.1	EDX71797.1	MC7420_1359	MC7420_6883	Transglycosylase SLT domain protein; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).	Penicillin-binding protein, 1A family; [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein).	0.628
EDX75441.1	EDX76688.1	MC7420_1359	MC7420_1691	Transglycosylase SLT domain protein; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).	Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase.	0.761
EDX76687.1	EDX76688.1	MC7420_1690	MC7420_1691	Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase.	0.799
EDX76688.1	EDX70989.1	MC7420_1691	MC7420_6589	Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase.	Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	0.869
EDX76688.1	EDX71299.1	MC7420_1691	MC7420_3414	Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase.	Glycosyl hydrolase family 9; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.	0.698
EDX76688.1	EDX71797.1	MC7420_1691	MC7420_6883	Putative peptidoglycan binding domain protein; [M] COG0860 N-acetylmuramoyl-L-alanine amidase.	Penicillin-binding protein, 1A family; [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein).	0.725

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Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006744

Ubiquinone biosynthetic process

5 of 17

2.0

2.63

2.61e-06

GO:0044249

Cellular biosynthetic process

8 of 722

0.57

0.35

0.0372

GO:1901576

Organic substance biosynthetic process

8 of 740

0.56

0.35

0.0389

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031177

Phosphopantetheine binding

2 of 2

2.53

0.79

0.0371

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3015

Ubiquinone metabolic process, and BolA protein

7 of 14

2.23

4.98

1.62e-11

CL:3017

Ubiquinone biosynthesis, and Flavoprotein

3 of 5

2.31

2.01

0.00015

CL:1189

Mixed, incl. Fatty acid metabolism, and AMP-binding, conserved site

3 of 44

1.36

0.68

0.0344

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00130

Ubiquinone and other terpenoid-quinone biosynthesis

6 of 70

1.46

1.89

3.16e-06

map01053

Biosynthesis of siderophore group nonribosomal peptides

3 of 35

1.46

0.92

0.0095

map01110

Biosynthesis of secondary metabolites

6 of 472

0.63

0.37

0.0472

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009366

Enterobactin synthetase complex

3 of 5

2.31

1.83

0.00034

GOCC:0110142

Ubiquinone biosynthesis complex

3 of 11

1.96

1.49

0.0011

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0831

Ubiquinone biosynthesis

3 of 6

2.23

1.8

0.00037

KW-0596

Phosphopantetheine

3 of 7

2.16

1.78

0.00037

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00501

AMP-binding enzyme

3 of 8

2.1

1.42

0.0019

PF00668

Condensation domain

2 of 3

2.35

0.88

0.0244

PF13193

AMP-binding enzyme C-terminal domain

2 of 5

2.13

0.79

0.0341

PF00550

Phosphopantetheine attachment site

2 of 6

2.05

0.79

0.0341

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR020806

Polyketide synthase, phosphopantetheine-binding domain

3 of 3

2.53

1.74

0.00061

IPR036736

ACP-like superfamily

3 of 7

2.16

1.44

0.0018

IPR020845

AMP-binding, conserved site

3 of 7

2.16

1.44

0.0018

IPR009081

Phosphopantetheine binding ACP domain

3 of 7

2.16

1.44

0.0018

IPR045851

AMP-binding enzyme, C-terminal domain superfamily

3 of 8

2.1

1.43

0.0018

(more ...)

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