STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDX71723.1Hypothetical protein; [G] COG2513 PEP phosphonomutase and related enzymes. (295 aa)    
Predicted Functional Partners:
EDX71977.1
2-methylcitrate synthase/citrate synthase II subfamily; [C] COG0372 Citrate synthase; Belongs to the citrate synthase family.
 
 0.957
EDX74979.1
Alcohol dehydrogenase, iron-containing family; [C] COG1012 NAD-dependent aldehyde dehydrogenases; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.848
EDX75767.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
    
  0.842
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.825
EDX75183.1
[G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.776
EDX76440.1
Aminotransferase, class V superfamily; [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.
  
 
 0.771
EDX71937.1
Aconitate hydratase, putative; [C] COG1048 Aconitase A.
 
 0.738
EDX71673.1
Hypothetical protein.
       0.718
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.689
EDX77721.1
CoA binding domain protein; [C] COG0074 Succinyl-CoA synthetase, alpha subunit.
    
 0.670
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
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