STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (319 aa)    
Predicted Functional Partners:
EDX77180.1
Homoserine dehydrogenase, NAD binding domain family; [E] COG0460 Homoserine dehydrogenase.
 
 0.990
EDX74629.1
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.974
EDX75244.1
[E] COG0498 Threonine synthase.
  
 
 0.950
EDX75670.1
Asparate kinase, monofunctional class, putative; [E] COG0527 Aspartokinases.
  
 0.946
purM
Phosphoribosylformylglycinamidine cyclo-ligase; [F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase.
 
    
 0.913
EDX72536.1
Pyridoxal-phosphate dependent enzyme superfamily; [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase.
  
 
 0.901
EDX72491.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.878
EDX73120.1
[E] COG0440 Acetolactate synthase, small (regulatory) subunit.
  
 
 0.839
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
  
 0.795
EDX73619.1
[E] COG0069 Glutamate synthase domain 2.
  
    0.755
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
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