STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDX77852.1uroporphyrin-III C-methyltransferase; [H] COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. (257 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.995
EDX77094.1
Sirohydrochlorin cobaltochelatase, putative; [S] COG2138 Uncharacterized conserved protein.
 
 
 0.960
EDX71204.1
[H] COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.945
EDX71161.1
Nitrite and sulphite reductase 4Fe-4S domain protein; [P] COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.937
EDX72775.1
uroporphyrin-III C-methyltransferase domain protein; [H] COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family.
 
 
0.912
EDX71646.1
precorrin-3B C17-methyltransferase domain protein; [H] COG1010 Precorrin-3B methylase.
 
0.908
EDX73304.1
[P] COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.906
EDX77584.1
[H] COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.902
EDX70996.1
[EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.891
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
 
  
 0.807
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
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