Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDX77183.1Hypothetical protein; [T] COG5635 Predicted NTPase (NACHT family); WD domain, G-beta repeat. (1312 aa)    
Predicted Functional Partners:
polA
DNA polymerase I superfamily; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.950
EDX77396.1
Hypothetical protein; [KL] COG1199 Rad3-related DNA helicases.
   
 0.907
EDX73211.1
Hypothetical protein; [J] COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.
    
 0.897
sbcD
Nuclease SbcCD, D subunit subfamily, putative; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 0.873
EDX74544.1
Ser/Thr protein phosphatase family protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
 0.873
EDX74651.1
Ser/Thr protein phosphatase family protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
 0.873
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.810
EDX78351.1
LAGLIDADG DNA endonuclease family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
   
 0.810
EDX76903.1
Mov34/MPN/PAD-1 family; [R] COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily.
   
 0.808
EDX71773.1
[RTKL] COG0515 Serine/threonine protein kinase; protein kinase domain, putative.
   
 0.791
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
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