STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDX72837.1KaiA binding family; [T] COG0467 RecA-superfamily ATPases implicated in signal transduction. (567 aa)    
Predicted Functional Partners:
EDX72889.1
KaiB domain protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
 
 
 
 0.976
kaiB
Circadian clock protein KaiB; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC; Belongs to the KaiB family.
 
 
 
 0.958
EDX76711.1
Hypothetical protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; KaiB domain, putative.
 
 
 
 0.954
EDX76781.1
Hypothetical protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; KaiB domain, putative.
 
 
 
 0.954
MC7420_50
Hypothetical protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; KaiB domain, putative.
 
 
 
 0.954
EDX70946.1
KaiB domain protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
 
 
 
 0.943
EDX71309.1
Circadian clock protein KaiA; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC he [...]
   
 
 0.910
sasA
ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs.
    
 
 0.867
EDX78219.1
PAS fold family; [R] COG0517 FOG: CBS domain.
   
 
 0.627
EDX71158.1
Hypothetical protein; [T] COG0784 FOG: CheY-like receiver; response regulator receiver domain, putative.
   
 
 0.610
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
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