STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDX77239.1Aminotransferase, classes I and II superfamily; [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. (426 aa)    
Predicted Functional Partners:
EDX72582.1
Beta-ketoacyl synthase, N-terminal domain protein; [Q] COG3321 Polyketide synthase modules and related proteins.
 
 0.981
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.947
EDX77342.1
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
   
 0.908
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
 0.907
EDX77289.1
Condensation domain protein; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.891
EDX72645.1
AMP-binding enzyme domain protein; [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 0.876
EDX72580.1
KR domain family; [Q] COG3321 Polyketide synthase modules and related proteins.
 
 0.875
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.872
EDX72594.1
Amino acid adenylation domain protein; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.872
EDX72552.1
Nonribosomal peptide synthase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 0.869
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
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