node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDX71584.1 | EDX72491.1 | MC7420_5209 | MC7420_3563 | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.825 |
EDX71584.1 | EDX72582.1 | MC7420_5209 | MC7420_2490 | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Beta-ketoacyl synthase, N-terminal domain protein; [Q] COG3321 Polyketide synthase modules and related proteins. | 0.884 |
EDX71584.1 | EDX72818.1 | MC7420_5209 | MC7420_3264 | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Malic enzyme, NAD binding domain protein; [C] COG0281 Malic enzyme. | 0.790 |
EDX71584.1 | EDX73619.1 | MC7420_5209 | MC7420_3793 | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | [E] COG0069 Glutamate synthase domain 2. | 0.878 |
EDX71584.1 | EDX75183.1 | MC7420_5209 | MC7420_2187 | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | [G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.758 |
EDX71584.1 | EDX75767.1 | MC7420_5209 | MC7420_6422 | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.891 |
EDX71584.1 | EDX76727.1 | MC7420_5209 | MC7420_1730 | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; [C] COG1012 NAD-dependent aldehyde dehydrogenases. | 0.852 |
EDX71584.1 | EDX77962.1 | MC7420_5209 | MC7420_7700 | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | [E] COG0069 Glutamate synthase domain 2. | 0.878 |
EDX71584.1 | dapB | MC7420_5209 | MC7420_5330 | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.759 |
EDX71584.1 | gcvP | MC7420_5209 | MC7420_2006 | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.817 |
EDX72491.1 | EDX71584.1 | MC7420_3563 | MC7420_5209 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 0.825 |
EDX72491.1 | EDX72582.1 | MC7420_3563 | MC7420_2490 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Beta-ketoacyl synthase, N-terminal domain protein; [Q] COG3321 Polyketide synthase modules and related proteins. | 0.848 |
EDX72491.1 | EDX72818.1 | MC7420_3563 | MC7420_3264 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Malic enzyme, NAD binding domain protein; [C] COG0281 Malic enzyme. | 0.864 |
EDX72491.1 | EDX73619.1 | MC7420_3563 | MC7420_3793 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | [E] COG0069 Glutamate synthase domain 2. | 0.473 |
EDX72491.1 | EDX75767.1 | MC7420_3563 | MC7420_6422 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.903 |
EDX72491.1 | EDX76727.1 | MC7420_3563 | MC7420_1730 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; [C] COG1012 NAD-dependent aldehyde dehydrogenases. | 0.846 |
EDX72491.1 | EDX77962.1 | MC7420_3563 | MC7420_7700 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | [E] COG0069 Glutamate synthase domain 2. | 0.473 |
EDX72491.1 | gcvP | MC7420_3563 | MC7420_2006 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.605 |
EDX72582.1 | EDX71584.1 | MC7420_2490 | MC7420_5209 | Beta-ketoacyl synthase, N-terminal domain protein; [Q] COG3321 Polyketide synthase modules and related proteins. | Aminotransferase, classes I and II superfamily; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 0.884 |
EDX72582.1 | EDX72491.1 | MC7420_2490 | MC7420_3563 | Beta-ketoacyl synthase, N-terminal domain protein; [Q] COG3321 Polyketide synthase modules and related proteins. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.848 |