STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDX73838.1Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (221 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
  
 
 0.988
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
   
 
 0.943
EDX76826.1
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
 
 0.889
EDX73999.1
DnaJ domain protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
 
 0.842
EDX76337.1
Hypothetical protein; [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases.
 
  
  0.802
EDX71664.1
UvrD/REP helicase domain protein; [L] COG0210 Superfamily I DNA and RNA helicases.
  
  
 0.801
EDX76427.1
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
   
 0.797
EDX77626.1
OstA-like protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
   
 0.780
EDX73328.1
Hypothetical protein; [R] COG1837 Predicted RNA-binding protein (contains KH domain).
  
     0.775
EDX73122.1
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.774
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
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