node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDX70881.1 | EDX78273.1 | MC7420_8091 | MC7420_8011 | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.643 |
EDX70881.1 | coaD | MC7420_8091 | MC7420_5739 | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.778 |
EDX70881.1 | coaE | MC7420_8091 | MC7420_6712 | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.609 |
EDX70881.1 | guaA | MC7420_8091 | MC7420_5214 | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | GMP synthase, C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 0.511 |
EDX70881.1 | nadE-2 | MC7420_8091 | MC7420_4909 | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | NAD synthase family; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.469 |
EDX71039.1 | EDX74006.1 | MC7420_6639 | MC7420_5886 | Putative methyltransferase; [L] COG0742 N6-adenine-specific methylase. | Hypothetical protein; [D] COG3599 Cell division initiation protein. | 0.415 |
EDX71039.1 | coaD | MC7420_6639 | MC7420_5739 | Putative methyltransferase; [L] COG0742 N6-adenine-specific methylase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.889 |
EDX73112.1 | EDX78273.1 | MC7420_4359 | MC7420_8011 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.700 |
EDX73112.1 | coaD | MC7420_4359 | MC7420_5739 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.671 |
EDX73112.1 | coaX | MC7420_4359 | MC7420_5492 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Transcriptional activator, putative, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.618 |
EDX73112.1 | guaA | MC7420_4359 | MC7420_5214 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | GMP synthase, C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 0.473 |
EDX73112.1 | nadE-2 | MC7420_4359 | MC7420_4909 | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | NAD synthase family; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.706 |
EDX74006.1 | EDX71039.1 | MC7420_5886 | MC7420_6639 | Hypothetical protein; [D] COG3599 Cell division initiation protein. | Putative methyltransferase; [L] COG0742 N6-adenine-specific methylase. | 0.415 |
EDX74006.1 | coaD | MC7420_5886 | MC7420_5739 | Hypothetical protein; [D] COG3599 Cell division initiation protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.706 |
EDX78273.1 | EDX70881.1 | MC7420_8011 | MC7420_8091 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | 0.643 |
EDX78273.1 | EDX73112.1 | MC7420_8011 | MC7420_4359 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.700 |
EDX78273.1 | coaD | MC7420_8011 | MC7420_5739 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.922 |
EDX78273.1 | coaE | MC7420_8011 | MC7420_6712 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.809 |
EDX78273.1 | coaX | MC7420_8011 | MC7420_5492 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Transcriptional activator, putative, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.921 |
coaD | EDX70881.1 | MC7420_5739 | MC7420_8091 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | 0.778 |