STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDX73992.1[H] COG1057 Nicotinic acid mononucleotide adenylyltransferase; Belongs to the NadD family. (188 aa)    
Predicted Functional Partners:
EDX73908.1
Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.950
nadE-2
NAD synthase family; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.940
EDX74505.1
Competence/damage-inducible protein CinA N-terminal domain, putative; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.
 
 
 0.916
EDX75934.1
Conserved hypothetical protein TIGR00488; [H] COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism.
  
 
 0.906
EDX72569.1
[H] COG0157 Nicotinate-nucleotide pyrophosphorylase.
    
 0.896
rsfS
Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.859
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.828
EDX74049.1
Hydrolase, NUDIX family protein; [F] COG1051 ADP-ribose pyrophosphatase.
    
 0.822
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
  
 
 0.814
EDX76299.1
Hypothetical protein; [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases.
   
 0.809
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
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