STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (322 aa)    
Predicted Functional Partners:
EDX71977.1
2-methylcitrate synthase/citrate synthase II subfamily; [C] COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 0.992
EDX75767.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
  
 
 0.990
EDX72582.1
Beta-ketoacyl synthase, N-terminal domain protein; [Q] COG3321 Polyketide synthase modules and related proteins.
  
 0.976
EDX75183.1
[G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.968
EDX77721.1
CoA binding domain protein; [C] COG0074 Succinyl-CoA synthetase, alpha subunit.
 
 0.956
EDX75345.1
[C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.953
EDX77856.1
ATP-grasp domain family; [C] COG0045 Succinyl-CoA synthetase, beta subunit.
 
 0.940
EDX74195.1
Hypothetical protein; [K] COG1396 Predicted transcriptional regulators.
  
 
 0.935
EDX78064.1
Hypothetical protein; [C] COG0538 Isocitrate dehydrogenases.
  
 
 0.923
EDX78208.1
Isocitrate dehydrogenase, NADP-dependent; [C] COG0538 Isocitrate dehydrogenases.
  
 
 0.923
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.