node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDX72852.1 | EDX76903.1 | MC7420_3298 | MC7420_1906 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | Mov34/MPN/PAD-1 family; [R] COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily. | 0.760 |
EDX72852.1 | EDX77180.1 | MC7420_3298 | MC7420_317 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | Homoserine dehydrogenase, NAD binding domain family; [E] COG0460 Homoserine dehydrogenase. | 0.734 |
EDX72852.1 | argG | MC7420_3298 | MC7420_6265 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | [E] COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.751 |
EDX72852.1 | argH | MC7420_3298 | MC7420_1211 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | [E] COG0165 Argininosuccinate lyase. | 0.727 |
EDX72852.1 | asd | MC7420_3298 | MC7420_3487 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.785 |
EDX72852.1 | dapA | MC7420_3298 | MC7420_3570 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.811 |
EDX72852.1 | dapB | MC7420_3298 | MC7420_5330 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.812 |
EDX72852.1 | glpK | MC7420_3298 | MC7420_8121 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.814 |
EDX72852.1 | lysA | MC7420_3298 | MC7420_6695 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.807 |
EDX72852.1 | murE | MC7420_3298 | MC7420_1900 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | UDP-N-acetylmuramyl-tripeptide synthetases subfamily; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.760 |
EDX76903.1 | EDX72852.1 | MC7420_1906 | MC7420_3298 | Mov34/MPN/PAD-1 family; [R] COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily. | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | 0.760 |
EDX76903.1 | glpK | MC7420_1906 | MC7420_8121 | Mov34/MPN/PAD-1 family; [R] COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.996 |
EDX76903.1 | lysA | MC7420_1906 | MC7420_6695 | Mov34/MPN/PAD-1 family; [R] COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.760 |
EDX77180.1 | EDX72852.1 | MC7420_317 | MC7420_3298 | Homoserine dehydrogenase, NAD binding domain family; [E] COG0460 Homoserine dehydrogenase. | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | 0.734 |
EDX77180.1 | argG | MC7420_317 | MC7420_6265 | Homoserine dehydrogenase, NAD binding domain family; [E] COG0460 Homoserine dehydrogenase. | [E] COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.758 |
EDX77180.1 | asd | MC7420_317 | MC7420_3487 | Homoserine dehydrogenase, NAD binding domain family; [E] COG0460 Homoserine dehydrogenase. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.982 |
EDX77180.1 | dapA | MC7420_317 | MC7420_3570 | Homoserine dehydrogenase, NAD binding domain family; [E] COG0460 Homoserine dehydrogenase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.897 |
EDX77180.1 | dapB | MC7420_317 | MC7420_5330 | Homoserine dehydrogenase, NAD binding domain family; [E] COG0460 Homoserine dehydrogenase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.722 |
EDX77180.1 | lysA | MC7420_317 | MC7420_6695 | Homoserine dehydrogenase, NAD binding domain family; [E] COG0460 Homoserine dehydrogenase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.903 |
argG | EDX72852.1 | MC7420_6265 | MC7420_3298 | [E] COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; [E] COG0019 Diaminopimelate decarboxylase. | 0.751 |