STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (498 aa)    
Predicted Functional Partners:
EDX71646.1
precorrin-3B C17-methyltransferase domain protein; [H] COG1010 Precorrin-3B methylase.
  
 0.999
EDX71759.1
precorrin-8X methylmutase subfamily; [H] COG2082 Precorrin isomerase.
  
 0.993
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.991
EDX75379.1
L-threonine-O-3-phosphate decarboxylase; [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.
 
 0.986
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 0.975
EDX75232.1
[H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase.
 
 
 0.972
EDX75971.1
precorrin-8X methylmutase subfamily; [H] COG2082 Precorrin isomerase.
  
 0.969
EDX72768.1
[H] COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.966
EDX77584.1
[H] COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.963
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.960
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
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