EDX74847.1 protein (Coleofasciculus chthonoplastes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EDX74847.1

Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters. (687 aa)

Predicted Functional Partners:

EDX75162.1

0.902

EDX78142.1

0.897

EDX77756.1

0.881

EDX73153.1

0.881

EDX78020.1

0.881

EDX70841.1

0.876

EDX75382.1

0.876

EDX70851.1

0.876

EDX71393.1

0.876

EDX77021.1

0.876

Your Current Organism:

Coleofasciculus chthonoplastes

NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDX70841.1	EDX70851.1	MC7420_130	MC7420_140	Hypothetical protein.	Hypothetical protein.	0.832
EDX70841.1	EDX74847.1	MC7420_130	MC7420_721	Hypothetical protein.	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	0.876
EDX70841.1	EDX75162.1	MC7420_130	MC7420_2166	Hypothetical protein.	GAF domain protein; [T] COG0784 FOG: CheY-like receiver.	0.505
EDX70851.1	EDX70841.1	MC7420_140	MC7420_130	Hypothetical protein.	Hypothetical protein.	0.832
EDX70851.1	EDX74847.1	MC7420_140	MC7420_721	Hypothetical protein.	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	0.876
EDX70851.1	EDX75162.1	MC7420_140	MC7420_2166	Hypothetical protein.	GAF domain protein; [T] COG0784 FOG: CheY-like receiver.	0.505
EDX71393.1	EDX74847.1	MC7420_1607	MC7420_721	Hypothetical protein.	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	0.876
EDX71393.1	EDX75162.1	MC7420_1607	MC7420_2166	Hypothetical protein.	GAF domain protein; [T] COG0784 FOG: CheY-like receiver.	0.505
EDX73153.1	EDX74847.1	MC7420_4400	MC7420_721	Miro-like protein; [S] COG4886 Leucine-rich repeat (LRR) protein.	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	0.881
EDX73153.1	EDX75162.1	MC7420_4400	MC7420_2166	Miro-like protein; [S] COG4886 Leucine-rich repeat (LRR) protein.	GAF domain protein; [T] COG0784 FOG: CheY-like receiver.	0.578
EDX74847.1	EDX70841.1	MC7420_721	MC7420_130	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	Hypothetical protein.	0.876
EDX74847.1	EDX70851.1	MC7420_721	MC7420_140	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	Hypothetical protein.	0.876
EDX74847.1	EDX71393.1	MC7420_721	MC7420_1607	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	Hypothetical protein.	0.876
EDX74847.1	EDX73153.1	MC7420_721	MC7420_4400	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	Miro-like protein; [S] COG4886 Leucine-rich repeat (LRR) protein.	0.881
EDX74847.1	EDX75162.1	MC7420_721	MC7420_2166	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	GAF domain protein; [T] COG0784 FOG: CheY-like receiver.	0.902
EDX74847.1	EDX75382.1	MC7420_721	MC7420_1300	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	GTPase, putative; [R] COG1100 GTPase SAR1 and related small G proteins.	0.876
EDX74847.1	EDX77021.1	MC7420_721	MC7420_2024	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	GTPase, putative; [R] COG1100 GTPase SAR1 and related small G proteins.	0.876
EDX74847.1	EDX77756.1	MC7420_721	MC7420_3080	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	Ras family, putative; [S] COG4886 Leucine-rich repeat (LRR) protein.	0.881
EDX74847.1	EDX78020.1	MC7420_721	MC7420_7758	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	Ras family, putative; [S] COG4886 Leucine-rich repeat (LRR) protein.	0.881
EDX74847.1	EDX78142.1	MC7420_721	MC7420_7880	Transporter, CPA2 family; [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.	[S] COG4886 Leucine-rich repeat (LRR) protein.	0.897

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

42

PPI enrichment p-value:

0.00908

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050567

glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity

3 of 3

2.49

1.87

0.00033

GO:0050566

asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity

2 of 2

2.49

1.04

0.0125

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1990

Starch and sucrose metabolism, and Amino acid/polyamine transporter I

4 of 12

2.01

8.28e-05

CL:2004

Alpha-amylase domain, and Amino acid/polyamine transporter I

2 of 5

2.09

0.76

0.0384

CL:1063

Biosynthesis of amino acids, and Ribonucleoside monophosphate biosynthetic process

5 of 156

0.99

0.6

0.0214

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

aai00500

Starch and sucrose metabolism

4 of 17

1.86

2.06

3.72e-05

aai00970

Aminoacyl-tRNA biosynthesis

3 of 25

1.57

1.09

0.0042

aai01100

Metabolic pathways

8 of 610

0.6

0.45

0.0042

aai01110

Biosynthesis of secondary metabolites

5 of 300

0.71

0.4

0.0445

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030956

glutamyl-tRNA(Gln) amidotransferase complex

2 of 3

2.31

0.86

0.0258

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0320

Glycogen biosynthesis

2 of 3

2.31

0.94

0.0185

KW-0648

Protein biosynthesis

3 of 41

1.35

0.69

0.0305

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR006047

Glycosyl hydrolase, family 13, catalytic domain

3 of 3

2.49

1.71

0.00068

IPR017853

Glycoside hydrolase superfamily

3 of 8

2.06

1.33

0.0028

IPR013780

Glycosyl hydrolase, all-beta

2 of 2

2.49

0.87

0.0255

IPR006048

Alpha-amylase/branching enzyme, C-terminal all beta

2 of 2

2.49

0.87

0.0255

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00642

Alpha-amylase domain

2 of 2

2.49

1.19

0.0065

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (18%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About