STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDX74860.13-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (418 aa)    
Predicted Functional Partners:
EDX70579.1
[I] COG0331 (acyl-carrier-protein) S-malonyltransferase.
 0.999
EDX72582.1
Beta-ketoacyl synthase, N-terminal domain protein; [Q] COG3321 Polyketide synthase modules and related proteins.
  
0.998
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 0.995
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.994
EDX71108.1
Amino acid adenylation domain protein; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
 0.993
EDX72580.1
KR domain family; [Q] COG3321 Polyketide synthase modules and related proteins.
 
 0.992
EDX72645.1
AMP-binding enzyme domain protein; [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 0.989
EDX77289.1
Condensation domain protein; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
 0.987
EDX70556.1
Condensation domain protein; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
 0.987
EDX72552.1
Nonribosomal peptide synthase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
 0.981
Your Current Organism:
Coleofasciculus chthonoplastes
NCBI taxonomy Id: 118168
Other names: C. chthonoplastes PCC 7420, Coleofasciculus chthonoplastes PCC 7420, Microcoleus chthonoplastes PCC 7420, Microcoleus sp. PCC 7420
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.