STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N307_13098WD repeat domain phosphoinositide-interacting protein 3. (322 aa)    
Predicted Functional Partners:
N307_13618
Autophagy-related protein 2 B.
    
 
 0.848
N307_07719
WD repeat domain phosphoinositide-interacting protein 2.
   
0.668
N307_12902
WD repeat domain phosphoinositide-interacting protein 1.
   
0.668
N307_08329
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
    
 
 0.667
N307_13097
Ras-related protein Rab-40B.
 
 
  
 0.647
N307_05545
Beclin-1.
    
 
 0.630
N307_03863
Tectonin beta-propeller repeat-containing protein 2.
   
  
 0.615
N307_04364
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
   
  
 0.606
N307_01061
Autophagy protein 5; Involved in autophagic vesicle formation.
      
 0.573
N307_06622
Autophagy-related protein 3.
   
  
 0.567
Your Current Organism:
Picoides pubescens
NCBI taxonomy Id: 118200
Other names: Dendrocopos pubescens, Downy woodpecker, Dryobates pubescens, P. pubescens
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.