STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N307_13697E3 UFM1-protein ligase 1. (791 aa)    
Predicted Functional Partners:
N307_12164
DDRGK domain-containing protein 1.
    
 
 0.947
N307_01778
Ubiquitin-like modifier-activating enzyme 5.
   
 
 0.819
N307_08329
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
   
 
 0.641
N307_11755
NEDD8-activating enzyme E1 catalytic subunit.
     
 0.640
N307_09246
Ubiquitin-conjugating enzyme E2 variant 3.
   
 
 0.615
N307_06770
Ufm1-specific protease 2.
   
  
 0.604
N307_09888
Adenylyltransferase and sulfurtransferase MOCS3.
     
 0.536
N307_00094
PRKC apoptosis WT1 regulator protein.
      
 0.513
N307_07745
Suppressor of G2 allele of SKP1.
      
 0.505
N307_01071
Translocation protein SEC63.
   
   0.469
Your Current Organism:
Picoides pubescens
NCBI taxonomy Id: 118200
Other names: Dendrocopos pubescens, Downy woodpecker, Dryobates pubescens, P. pubescens
Server load: low (14%) [HD]