STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N307_02190Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (202 aa)    
Predicted Functional Partners:
N307_00208
Very-long-chain enoyl-CoA reductase.
   
 0.967
N307_13307
Trans-2,3-enoyl-CoA reductase-like.
   
 0.915
N307_12333
Elongation of very long chain fatty acids protein.
     
 0.884
N307_11202
Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.872
N307_05668
Hydroxysteroid dehydrogenase-like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.872
ELOVL5
Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...]
    
 0.869
N307_01561
Elongation of very long chain fatty acids protein.
    
 0.869
N307_11802
Elongation of very long chain fatty acids protein.
    
 0.869
N307_12037
Elongation of very long chain fatty acids protein.
    
 0.869
N307_11203
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter.
   
 0.863
Your Current Organism:
Picoides pubescens
NCBI taxonomy Id: 118200
Other names: Dendrocopos pubescens, Downy woodpecker, Dryobates pubescens, P. pubescens
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