STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N307_04757E3 ubiquitin-protein ligase HECTD3. (709 aa)    
Predicted Functional Partners:
N307_08153
E3 ubiquitin-protein ligase TRIP12.
   
 
0.771
N307_02227
Ubiquitin-40S ribosomal protein S27a.
   
 0.727
N307_07331
Polyubiquitin-B.
   
 0.709
N307_14851
2'-5'-oligoadenylate synthase-like 2.
   
 0.709
N307_00856
Polyubiquitin-C.
   
 0.709
N307_06670
Phosphoglucomutase-2; Belongs to the phosphohexose mutase family.
   
    0.601
N307_15395
Ubiquitin-like 7.
   
 0.571
N307_02326
Ubiquilin-1.
   
 0.571
N307_08329
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
    
 0.545
N307_13071
THO complex subunit 4.
    
 
 0.544
Your Current Organism:
Picoides pubescens
NCBI taxonomy Id: 118200
Other names: Dendrocopos pubescens, Downy woodpecker, Dryobates pubescens, P. pubescens
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.