node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
N307_00716 | PPARG | A0A093GPK6 | A0A093GPP6 | Lysine-specific demethylase 3B. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.889 |
N307_00799 | N307_04713 | A0A093GU44 | A0A093GN82 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoic acid receptor RXR-gamma. | 0.923 |
N307_00799 | N307_04836 | A0A093GU44 | A0A093J373 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoic acid receptor RXR-alpha. | 0.923 |
N307_00799 | N307_07335 | A0A093GU44 | A0A093GRP8 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 1. | 0.719 |
N307_00799 | N307_13277 | A0A093GU44 | A0A093GKV8 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | CREB-binding protein. | 0.800 |
N307_00799 | N307_13467 | A0A093GU44 | A0A093GV82 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha. | 0.510 |
N307_00799 | N307_14741 | A0A093GU44 | A0A093J873 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 0 group B member 2. | 0.719 |
N307_00799 | N307_15512 | A0A093GU44 | A0A093G9Y9 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Histone deacetylase 3. | 0.584 |
N307_00799 | PPARG | A0A093GU44 | A0A093GPP6 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.986 |
N307_04713 | N307_00799 | A0A093GN82 | A0A093GU44 | Retinoic acid receptor RXR-gamma. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.923 |
N307_04713 | N307_04836 | A0A093GN82 | A0A093J373 | Retinoic acid receptor RXR-gamma. | Retinoic acid receptor RXR-alpha. | 0.834 |
N307_04713 | N307_07335 | A0A093GN82 | A0A093GRP8 | Retinoic acid receptor RXR-gamma. | Nuclear receptor corepressor 1. | 0.959 |
N307_04713 | N307_13277 | A0A093GN82 | A0A093GKV8 | Retinoic acid receptor RXR-gamma. | CREB-binding protein. | 0.898 |
N307_04713 | N307_13467 | A0A093GN82 | A0A093GV82 | Retinoic acid receptor RXR-gamma. | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha. | 0.460 |
N307_04713 | N307_15512 | A0A093GN82 | A0A093G9Y9 | Retinoic acid receptor RXR-gamma. | Histone deacetylase 3. | 0.794 |
N307_04713 | PPARG | A0A093GN82 | A0A093GPP6 | Retinoic acid receptor RXR-gamma. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.960 |
N307_04836 | N307_00799 | A0A093J373 | A0A093GU44 | Retinoic acid receptor RXR-alpha. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.923 |
N307_04836 | N307_04713 | A0A093J373 | A0A093GN82 | Retinoic acid receptor RXR-alpha. | Retinoic acid receptor RXR-gamma. | 0.834 |
N307_04836 | N307_07335 | A0A093J373 | A0A093GRP8 | Retinoic acid receptor RXR-alpha. | Nuclear receptor corepressor 1. | 0.959 |
N307_04836 | N307_13277 | A0A093J373 | A0A093GKV8 | Retinoic acid receptor RXR-alpha. | CREB-binding protein. | 0.898 |