STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N307_12813Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)    
Predicted Functional Partners:
N307_00887
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
   
 0.991
N307_08608
cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily.
    
 0.960
N307_05642
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1.
   
 0.952
N307_02382
cAMP-dependent protein kinase catalytic subunit PRKX.
    
  0.910
N307_03688
Calcium-transporting ATPase type 2C member 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
    
 0.866
N307_00620
Calcium-transporting ATPase type 2C member 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
    
 0.866
N307_13867
THAP domain-containing protein 1.
    
  0.843
N307_03986
Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
    
 0.824
N307_09176
Sodium/potassium-transporting ATPase subunit alpha.
    
 0.732
N307_04568
Potassium-transporting ATPase alpha chain 1.
    
 0.732
Your Current Organism:
Picoides pubescens
NCBI taxonomy Id: 118200
Other names: Dendrocopos pubescens, Downy woodpecker, Dryobates pubescens, P. pubescens
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.