STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N307_02345Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (613 aa)    
Predicted Functional Partners:
N307_11574
Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.
    
 0.906
N307_03823
Platelet-derived growth factor C.
    
 0.891
N307_11725
Angiopoietin-2.
   
 0.889
N307_11337
Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family.
    
 0.887
N307_13161
Growth factor receptor-bound protein 2.
    
 0.878
N307_05098
Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.
   
 0.877
N307_00735
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
   
 0.868
N307_10339
Angiopoietin-1.
   
 0.868
N307_14338
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
    
 0.862
N307_00575
Neuropilin; Belongs to the neuropilin family.
    
 0.862
Your Current Organism:
Picoides pubescens
NCBI taxonomy Id: 118200
Other names: Dendrocopos pubescens, Downy woodpecker, Dryobates pubescens, P. pubescens
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.