N307_03517 protein (Picoides pubescens) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Gene Fusion

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[Homology]

Score

N307_03517

Uncharacterized protein. (284 aa)

Predicted Functional Partners:

N307_15379

0.822

N307_12680

0.744

N307_03383

0.688

N307_05537

0.678

N307_11128

0.618

N307_06551

0.604

N307_03621

0.604

N307_14594

0.598

N307_12244

0.583

N307_01426

0.575

Your Current Organism:

Picoides pubescens

NCBI taxonomy Id: 118200
Other names: Dendrocopos pubescens, Downy woodpecker, Dryobates pubescens, P. pubescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N307_01426	N307_03517	A0A093IZX6	A0A093GUY9	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.575
N307_01426	N307_12680	A0A093IZX6	A0A093GHH7	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Pantothenate kinase 3.	0.574
N307_03383	N307_03517	A0A093J678	A0A093GUY9	Coiled-coil domain-containing protein 30.	Uncharacterized protein.	0.688
N307_03383	N307_03621	A0A093J678	A0A093IUK2	Coiled-coil domain-containing protein 30.	Growth arrest-specific protein 8.	0.688
N307_03383	N307_05537	A0A093J678	A0A093G2C1	Coiled-coil domain-containing protein 30.	Max-like X.	0.822
N307_03383	N307_06551	A0A093J678	A0A093G334	Coiled-coil domain-containing protein 30.	Pantothenate kinase 4; Belongs to the type II pantothenate kinase family.	0.927
N307_03383	N307_11128	A0A093J678	A0A093ITI5	Coiled-coil domain-containing protein 30.	Thymidylate synthase.	0.854
N307_03383	N307_12680	A0A093J678	A0A093GHH7	Coiled-coil domain-containing protein 30.	Pantothenate kinase 3.	0.688
N307_03383	N307_15379	A0A093J678	A0A093GA64	Coiled-coil domain-containing protein 30.	Phosphopantothenoylcysteine decarboxylase.	0.937
N307_03517	N307_01426	A0A093GUY9	A0A093IZX6	Uncharacterized protein.	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.575
N307_03517	N307_03383	A0A093GUY9	A0A093J678	Uncharacterized protein.	Coiled-coil domain-containing protein 30.	0.688
N307_03517	N307_03621	A0A093GUY9	A0A093IUK2	Uncharacterized protein.	Growth arrest-specific protein 8.	0.604
N307_03517	N307_05537	A0A093GUY9	A0A093G2C1	Uncharacterized protein.	Max-like X.	0.678
N307_03517	N307_06551	A0A093GUY9	A0A093G334	Uncharacterized protein.	Pantothenate kinase 4; Belongs to the type II pantothenate kinase family.	0.604
N307_03517	N307_11128	A0A093GUY9	A0A093ITI5	Uncharacterized protein.	Thymidylate synthase.	0.618
N307_03517	N307_12244	A0A093GUY9	A0A093G2K4	Uncharacterized protein.	Putative ATP-dependent RNA helicase DHX33.	0.583
N307_03517	N307_12680	A0A093GUY9	A0A093GHH7	Uncharacterized protein.	Pantothenate kinase 3.	0.744
N307_03517	N307_14594	A0A093GUY9	A0A093H6H3	Uncharacterized protein.	Axonemal dynein light intermediate polypeptide 1.	0.598
N307_03517	N307_15379	A0A093GUY9	A0A093GA64	Uncharacterized protein.	Phosphopantothenoylcysteine decarboxylase.	0.822
N307_03621	N307_03383	A0A093IUK2	A0A093J678	Growth arrest-specific protein 8.	Coiled-coil domain-containing protein 30.	0.688

page 1 of 4

Network Stats

number of nodes:

4

number of edges:

3

average node degree:

1.5

avg. local clustering coefficient:

0.75

expected number of edges:

3

PPI enrichment p-value:

0.562

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1903778

Protein localization to vacuolar membrane

2 of 3

3.29

1.64

0.0011

GO:0010994

Free ubiquitin chain polymerization

2 of 4

3.16

1.64

0.0011

GO:0008283

Cell population proliferation

2 of 4

3.16

1.64

0.0011

GO:0070534

Protein K63-linked ubiquitination

2 of 6

2.99

1.63

0.0011

GO:2001234

Negative regulation of apoptotic signaling pathway

2 of 8

2.86

1.61

0.0012

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0061631

Ubiquitin conjugating enzyme activity

4 of 24

2.68

3.52

2.61e-07

GO:0004842

Ubiquitin-protein transferase activity

5 of 177

1.91

2.64

1.43e-06

GO:0004869

Cysteine-type endopeptidase inhibitor activity

2 of 4

3.16

1.81

0.00054

GO:0140096

Catalytic activity, acting on a protein

6 of 1625

1.03

0.83

0.0018

GO:0016740

Transferase activity

6 of 1899

0.96

0.74

0.0031

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031371

Ubiquitin conjugating enzyme complex

2 of 5

3.06

1.53

0.0017

GO:0005819

Spindle

3 of 73

2.08

1.44

0.0017

GO:0000922

Spindle pole

2 of 14

2.62

1.34

0.0035

GO:0030496

Midbody

2 of 26

2.35

1.13

0.0083

GO:0005802

trans-Golgi network

2 of 28

2.32

1.12

0.0083

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3111

IRAK2 mediated activation of TAK1 complex, and Ubiquitin conjugating enzyme activity

4 of 14

2.92

3.87

7.40e-08

CL:3091

Mixed, incl. Ubiquitin conjugating enzyme activity, and Formation of Incision Complex in GG-NER

5 of 77

2.28

3.54

7.40e-08

CL:3127

Protein localization to vacuolar membrane, and Ubiquitin conserved site

2 of 5

3.06

1.76

0.00065

CL:3113

IRAK2 mediated activation of TAK1 complex, and Cell population proliferation

2 of 5

3.06

1.76

0.00065

CL:629

Small GTPase mediated signal transduction, and Pleckstrin homology domain

2 of 43

2.13

0.85

0.0259

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04120

Ubiquitin mediated proteolysis

6 of 262

1.82

3.1

2.22e-08

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9646399

Aggrephagy

2 of 24

2.38

0.81

0.0334

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031372

UBC13-MMS2 complex

2 of 3

3.29

1.64

0.0011

GOCC:0030496

Midbody

2 of 6

2.99

1.55

0.0016

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000608

Ubiquitin-conjugating enzyme E2

3 of 24

2.56

1.91

0.00030

IPR016135

Ubiquitin-conjugating enzyme/RWD-like

3 of 31

2.45

1.88

0.00031

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00212

Ubiquitin-conjugating enzyme E2, catalytic domain homologues

3 of 24

2.56

2.42

3.10e-05

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