STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N307_15055E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa)    
Predicted Functional Partners:
N307_02931
Calcyclin-binding protein.
    
 0.956
N307_01802
Catenin beta-1.
    
 0.880
N307_03977
Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.815
N307_02293
Ubiquitin-conjugating enzyme E2 variant 2.
    
   0.788
N307_04589
Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.779
N307_12611
Ubiquitin-conjugating enzyme E2 D2.
    
 0.779
N307_10761
Ubiquitin-conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.779
N307_04327
Alpha-synuclein; Belongs to the synuclein family.
    
 0.726
N307_04197
Ubiquitin-conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.716
N307_08948
Ubiquitin-conjugating enzyme E2 E1.
    
 0.716
Your Current Organism:
Picoides pubescens
NCBI taxonomy Id: 118200
Other names: Dendrocopos pubescens, Downy woodpecker, Dryobates pubescens, P. pubescens
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