STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N307_00544Disco-interacting protein 2 C. (1471 aa)    
Predicted Functional Partners:
N307_00697
Uncharacterized protein.
   
 0.964
N307_12273
Hydroxysteroid dehydrogenase-like 2.
  
 0.864
N307_12272
Hydroxysteroid dehydrogenase-like 2.
  
 0.864
N307_01572
Partner and localizer of BRCA2.
  
 0.860
N307_01571
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.860
N307_09170
E3 SUMO-protein ligase RanBP2.
   
 0.838
N307_09171
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.838
MED15
Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.804
N307_02372
Mediator of RNA polymerase II transcription subunit 23.
    
 0.802
N307_06776
Cytochrome P450 4V2; Belongs to the cytochrome P450 family.
  
 0.799
Your Current Organism:
Picoides pubescens
NCBI taxonomy Id: 118200
Other names: Dendrocopos pubescens, Downy woodpecker, Dryobates pubescens, P. pubescens
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.