STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A1O3_040823-hydroxy-3-methylglutaryl coenzyme A reductase. (1150 aa)    
Predicted Functional Partners:
A1O3_05127
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.992
A1O3_07943
Squalene monooxygenase.
   
  
 0.925
A1O3_08518
Cytochrome P450, family 51 (Sterol 14-demethylase); Belongs to the cytochrome P450 family.
   
  
 0.920
A1O3_08852
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
  
 0.914
A1O3_05880
Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.
  
 
 0.907
A1O3_07668
Uncharacterized protein.
   
 
 0.900
A1O3_09472
RING-type domain-containing protein.
   
 
 0.882
A1O3_04914
Uncharacterized protein.
    
 0.835
A1O3_00394
Uncharacterized protein.
   
 
 0.793
A1O3_05627
Uncharacterized protein; Involved in DNA replication and cell separation. Belongs to the SDS23 family.
    
 0.786
Your Current Organism:
Capronia epimyces
NCBI taxonomy Id: 1182542
Other names: C. epimyces CBS 606.96, Capronia epimyces CBS 606.96
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