STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mshCcysteine--1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase MshC; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (461 aa)    
Predicted Functional Partners:
cysE
Serine acetyltransferase.
 
 
 0.837
mshD
Acetyltransferase MshD; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
 
  
 0.829
cysK
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.778
mshB
N-acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB; Belongs to the MshB deacetylase family.
 
 
 0.764
GAB94534.1
Hypothetical protein.
 
     0.761
GAB94533.1
Hypothetical protein.
 
     0.755
mca
Mycothiol conjugate amidase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
 
  
 0.736
cysS
cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 
0.712
cysS-2
cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 
0.707
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.706
Your Current Organism:
Kineosphaera limosa
NCBI taxonomy Id: 1184609
Other names: K. limosa NBRC 100340, Kineosphaera limosa Lpha5, Kineosphaera limosa NBRC 100340, Kineosphaera limosa str. NBRC 100340, Kineosphaera limosa strain NBRC 100340, [uncultured] High G+C Gram-positive bacterium Lpha5
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