STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucDsuccinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
sucA
2-oxoglutarate dehydrogenase E1 component.
 0.991
GAB94249.1
Putative pyruvate--ferredoxin oxidoreductase.
  
 
 0.981
GAB96566.1
Hypothetical protein.
  
 
 0.978
GAB95070.1
Putative dihydrolipoamide acyltransferase.
 0.964
sdhB
Succinate dehydrogenase iron-sulfur subunit.
  
 0.963
sdhB-2
Succinate dehydrogenase iron-sulfur subunit.
  
 0.963
gltB
Glutamate synthase large subunit.
  
 
 0.950
GAB96084.1
Putative fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.943
nadB
L-aspartate oxidase.
 0.928
Your Current Organism:
Kineosphaera limosa
NCBI taxonomy Id: 1184609
Other names: K. limosa NBRC 100340, Kineosphaera limosa Lpha5, Kineosphaera limosa NBRC 100340, Kineosphaera limosa str. NBRC 100340, Kineosphaera limosa strain NBRC 100340, [uncultured] High G+C Gram-positive bacterium Lpha5
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.