STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaAPantothenate kinase (Pantothenic acid kinase). (307 aa)    
Predicted Functional Partners:
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
     
 0.916
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.683
fhs
Formate--tetrahydrofolate ligase (Formyltetrahydrofolate synthetase).
      
 0.536
A11Y_20516
DUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  
  
  0.521
birA
Biotin operon repressor / biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.516
EJN55849.1
Pyrimidine-nucleoside phosphorylase.
    
  0.509
rpiA
Ribose-5-phosphate isomerase A 2 (Phosphoriboisomerase A 2); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
  
  0.505
EJN55650.1
Putative nucleotide phosphoesterase; Belongs to the 5'-nucleotidase family.
    
  0.493
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
    
  0.471
Your Current Organism:
Lactobacillus coryniformis
NCBI taxonomy Id: 1185325
Other names: L. coryniformis subsp. coryniformis CECT 5711, Lactobacillus coryniformis subsp. coryniformis CECT 5711, Lactobacillus coryniformis subsp. coryniformis str. CECT 5711, Lactobacillus coryniformis subsp. coryniformis strain CECT 5711
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