STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IER3Radiation-inducible immediate-early gene IEX-1. (156 aa)    
Predicted Functional Partners:
ZFP36
Tristetraprolin.
   
  
 0.628
PPP2R5C
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
    
 0.589
PPP2R5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
    
 0.588
MAPK1
Mitogen-activated protein kinase 1 isoform X1.
    
 0.586
MAPK3
Mitogen-activated protein kinase.
    
 0.586
TMEM229B
Transmembrane protein 229B isoform X1.
      
 0.513
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog isoform X1.
  
 
 
 0.491
TNFAIP3
Tumor necrosis factor alpha-induced protein 3.
   
  
 0.478
IER2
Immediate early response gene 2 protein.
   
  
 0.478
NFKBIA
NF-kappa-B inhibitor alpha.
   
  
 0.477
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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