STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MZF1Myeloid zinc finger 1 isoform X1. (735 aa)    
Predicted Functional Partners:
SNAPC4
snRNA-activating protein complex subunit 4.
   
 
  0.561
RFX3
Transcription factor RFX3 isoform X1.
    
 
 0.502
GATA1
Erythroid transcription factor.
    
 0.492
SPZ1
Spermatogenic leucine zipper protein 1.
    
 0.483
NKX6-3
Homeobox protein Nkx-6.3.
      
 0.457
NRBP1
Nuclear receptor-binding protein.
      
 0.450
IRF2
LOW QUALITY PROTEIN: interferon regulatory factor 2.
    
 0.443
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.441
BACH2
Transcription regulator protein BACH2.
      
 0.438
HSP90B1
Endoplasmin.
    
 0.431
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.