STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTS6-pyruvoyl tetrahydrobiopterin synthase. (145 aa)    
Predicted Functional Partners:
GCH1
GTP cyclohydrolase 1 isoform X1.
  
 
 0.992
SPR
Sepiapterin reductase.
  
 
 0.986
CBR1
Carbonyl reductase [NADPH] 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.924
AKR1B1
Aldose reductase isoform X1.
    
 0.902
LOC103069218
Dihydrodiol dehydrogenase 3-like.
    
 0.902
ALPL
Alkaline phosphatase.
     
  0.900
ALPI
Alkaline phosphatase.
     
  0.900
PRKG2
cGMP-dependent protein kinase.
    
  0.869
GCHFR
GTP cyclohydrolase 1 feedback regulatory protein.
     
 0.691
PRKG1
cGMP-dependent protein kinase.
    
  0.573
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.