STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKF06167.1Hydrogenase expression/formation protein HypD; KEGG: pgi:PG0073 0.95 orotidine 5'-monophosphate decarboxylase; K01591 orotidine-5'-phosphate decarboxylase; Psort location: Cytoplasmic, score: 8.96. (393 aa)    
Predicted Functional Partners:
EKF06168.1
Hydrogenase assembly chaperone HypC/HupF; KEGG: pla:Plav_3266 0.19 anhydro-N-acetylmuramic acid kinase; K09001 anhydro-N-acetylmuramic acid kinase.
 
 
 0.998
EKF06164.1
KEGG: npu:Npun_R0359 5.7e-165 hydrogenase expression/formation protein HypE K04655; Psort location: Cytoplasmic, score: 8.96.
 
 0.997
EKF06162.1
Hydrogenase accessory protein HypB; KEGG: cgl:NCgl0088 1.1e-08 cgl0089; Ni2+-binding GTPase K03189; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.966
EKF06169.1
KEGG: ecm:EcSMS35_2835 4.1e-146 hypF; [NiFe] hydrogenase maturation protein HypF K04656; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.950
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.914
EKF03285.1
Protein phosphatase 2C Ptc2; KEGG: spo:SPCC1223.11 0.61 ptc2;K01090.
 
  
 0.879
EKE99070.1
KEGG: npu:Npun_F0369 1.9e-276 nickel-dependent hydrogenase, large subunit, HupL K06281.
 
 
 0.877
EKE99069.1
Hydrogenase small subunit; KEGG: ana:all0688 5.9e-154 [NiFe] uptake hydrogenase small subunit; K06282 hydrogenase small subunit; Psort location: Periplasmic, score: 9.44.
 
   
 0.821
EKF02099.1
KEGG: ava:Ava_4661 1.0e-220 nickel-dependent hydrogenase, large subunit K00436; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.816
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
  
 0.782
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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