STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (505 aa)    
Predicted Functional Partners:
EKF01185.1
KEGG: npu:Npun_F1347 3.5e-94 glutamine amidotransferase of anthranilate synthase K01658; Psort location: Cytoplasmic, score: 9.97.
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 0.999
trpC
KEGG: ava:Ava_1926 1.2e-116 trpC; indole-3-glycerol-phosphate synthase K01609; Belongs to the TrpC family.
 0.998
EKF00288.1
Glycosyl transferase family, helical bundle domain protein; KEGG: npu:Npun_F1535 1.4e-154 glycosyl transferase family protein.
 
 0.996
trpF
KEGG: ava:Ava_2538 2.2e-83 N-(5'-phosphoribosyl)anthranilate isomerase K01817; Belongs to the TrpF family.
 
 
 0.985
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.971
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.969
EKF05973.1
Hypothetical protein; KEGG: npu:Npun_F3519 0.0024 cyclic nucleotide-regulated ABC bacteriocin/lantibiotic exporter.
  
 0.964
EKE98653.1
KEGG: ani:AN5186.2 8.2e-05 hypothetical protein; K11841 ubiquitin carboxyl-terminal hydrolase 10.
  
 0.964
EKF02861.1
Hypothetical protein; KEGG: dpo:Dpse_GA20829 0.48 GA20829 gene product from transcript GA20829-RA; K08585 calpain, invertebrate.
  
 0.964
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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