Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (329 aa)    
Predicted Functional Partners:
EKE97447.1
AMP-binding enzyme; KEGG: ava:Ava_1613 0. non-ribosomal peptide synthase.
  
 0.897
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
 
    0.829
EKE99922.1
Non-ribosomal peptide synthetase; KEGG: npu:Npun_R3431 0. amino acid adenylation domain-containing protein; Psort location: CytoplasmicMembrane, score: 8.46.
  
  0.810
EKF01144.1
AMP-binding enzyme; KEGG: npu:Npun_F2181 0. amino acid adenylation domain-containing protein.
  
 0.807
EKF06121.1
AMP-binding enzyme; KEGG: npu:Npun_R3431 1.6e-248 amino acid adenylation domain-containing protein.
  
  0.796
EKF03257.1
AMP-binding enzyme; KEGG: ava:Ava_1613 0. non-ribosomal peptide synthase; Psort location: CytoplasmicMembrane, score: 8.46.
  
  0.796
EKE97866.1
AMP-binding enzyme; KEGG: npu:Npun_R6588 0. amino acid adenylation domain-containing protein; Psort location: Cytoplasmic, score: 9.97; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  0.796
EKE97842.1
Thioesterase domain protein; KEGG: npu:Npun_R5497 5.2e-75 amino acid adenylation domain-containing protein; Psort location: Cytoplasmic, score: 9.26.
  
  0.796
EKE96453.1
KEGG: npu:Npun_F3359 5.4e-233 beta-ketoacyl synthase; Psort location: CytoplasmicMembrane, score: 9.82.
    
  0.769
pth
aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.763
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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