Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EKF05583.1Hypothetical protein; KEGG: rer:RER_10290 0.85 two-component histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. (151 aa)    
Predicted Functional Partners:
EKF00179.1
Tyrosine decarboxylase family protein; KEGG: cyh:Cyan8802_0909 2.9e-193 aromatic-L-amino-acid decarboxylase; Psort location: Cytoplasmic, score: 8.96.
    
 0.880
gyrB
DNA topoisomerase; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.744
EKE97400.1
KEGG: ava:Ava_3046 0. ferredoxin (flavodoxin) oxidoreductase K03737.
  
  
 0.729
EKF00361.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
  
  
 0.729
EKF01682.1
Hypothetical protein; KEGG: bxe:Bxe_B2895 0.063 succinate dehydrogenase subunit C K00241; Psort location: CytoplasmicMembrane, score: 9.82.
  
  
 0.724
EKF03477.1
Putative amidinotransferase; KEGG: hma:rrnAC0132 2.7e-87 lysine-ketoglutarate reductase/saccharopine dehydrogenase K00293; Psort location: Cytoplasmic, score: 8.96.
     
  0.708
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 
 0.676
EKF03236.1
Putative helicase; KEGG: hsl:OE8016F 8.1e-51 ATP-dependent helicase; Psort location: Cytoplasmic, score: 8.96.
    
 0.668
EKF01001.1
Hypothetical protein; KEGG: cgt:cgR_1633 0.080 phosphoenolpyruvate carboxylase K01595.
    
 0.668
EKF00793.1
KEGG: hau:Haur_4088 8.2e-70 silent information regulator protein Sir2; K12410 NAD-dependent deacetylase.
    
 0.625
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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